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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Nat Neurosci. 2012 Jun;15(6):816–818. doi: 10.1038/nn.3100

Fig. 1. dMSN stimulation induces persistentreinforcement, while iMSN stimulation induces transient punishment.

Fig. 1

(a, b) percent of contacts with the laser-paired trigger across each session for dMSN-ChR2 (green) and iMSN-ChR2 (red) mice (2-min bins). (c, d) percent of contacts with the laser-paired trigger during retraining and extinction sessions (2-min bins). (e, f) probability of subsequent contact with the laser-paired trigger following a previous trigger activation, for dMSN-ChR2, YFP control, and iMSN-ChR2 mice. (g) peri-event time histogram of velocity for dMSN-ChR2 and iMSN-ChR2 mice following contact with the laser-paired (blue) or inactive (grey) triggers. Time of stimulation for the laser-paired trigger shown in blue. Error bars in all panels represent standard error of the mean.