The first set of bars reflects current conditions. The next four sets of bars each reflect the impact of a single change to current conditions. In (1), improvements in screening increase clinical recognition rates to 80%. In (2), depression treatment is initiated in 80% of those recognized. In (3), treatment quality is improved, with 80% of those initiating treatment now receiving best-practices treatment. In (4), new treatments are developed with 80% efficacy. The final set of bars shows the impact of achieving (1), (2), and (3) simultaneously.