Fig. 4.

Effects of kisspeptin on pulse intervals. A, Schematic of the predicted result if kisspeptin were to have no effect on the timing of endogenous pulses. Note that this is an idealized schematic and that actual pulse profiles show more variability in pulse intervals. A, Interval between endogenous pulses before kisspeptin; B, interval between the endogenous pulses immediately preceding and following the kisspeptin-induced pulse; B1, interval between the kisspeptin-induced pulse and the immediately preceding endogenous pulse; B2, interval between the kisspeptin-induced pulse and the immediately following endogenous pulse; C, interval between endogenous pulses after kisspeptin. B, Observed pulse intervals. Bars, Means. NS, Not significant.