Table 3.
RR of thyroid cancer with selected thyroid disorders diagnosed at least 5 yr before thyroid cancer by attained age in male White and Black U.S. veterans
| Disorder | Attained age (yr) |
Pb | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| <50 |
50–69 |
≥70 |
||||||||
| n | RRa | 95% CI | n | RR | 95% CI | n | RR | 95% CI | ||
| Any thyroid gland disorder | 14 | 24.2 | 14.0–41.9 | 28 | 8.1 | 5.5–12.0 | 11 | 6.2 | 3.3–11.4 | 0.003 |
| Any goiter | 11 | 24.8 | 13.4–45.7 | 18 | 8.5 | 5.3–13.6 | 9 | 9.5 | 4.8–18.6 | 0.04 |
| Nontoxic nodular goiter | 7 | 94.8 | 44.5–202.0 | 16 | 24.9 | 15.1–41.1 | 5 | 13.4 | 5.5–32.6 | 0.005 |
| Simple and unspecified goiter | 4 | 63.3 | 23.5–170.5 | 5 | 14.4 | 6.0–34.9 | 5 | 27.4 | 11.2–66.7 | 0.11 |
| Hypothyroidism | 5 | 24.8 | 10.2–60.4 | 11 | 5.9 | 3.3–6.2 | 3 | 2.5 | 0.8–7.9 | 0.008 |
n, Number of cases of thyroid cancer with disorder of interest.
a
RR adjusted for calendar time, time on study, race, and number of hospitalizations by stratification.
b
P likelihood ratio-based test of interaction between attained age and disorder of interest.