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. 2012 Jul 25;2012:830703. doi: 10.1155/2012/830703

Table 1.

Lineage-specific mutant and transgenic lines for zebrafish hematopoiesis research.

Lineage Marker Mutant lines Transgenic lines
Mutant designation and mutation type References Line designation References
Hemangioblast tal1/scl t21384, K183X [38] PAC-tal1:GFP 5.0tal1:EGFP [39, 40]
lmo2 None lmo2:EGFP lmo2:DsRed [41]

EMPs runx1 hg1, W84X [42, 43] runx1P1:EGFP [44]

runx1 hg1, W84X [42, 43] runx1P2:EGFP [44]
HSCs cmyb t25217, I181N
hkz3, truncation in transactivation domain
[45]
[46]
cmyb:EGFP Developed by the Zon lab, used in [47]
cd41 None cd41:GFP [33, 34]

Erythropoiesis gata1 m651 (vlad tepes), R339X
hg2, T301K
[23]
[48]
gata1:GFP gata1:DsRed [37, 49]

Myelopoiesis: GMPs spi1/pu.1 None spi1:EGFP zpu.1:EGFP [50, 51]

mpx None mpx:GFP [52]
Myelopoiesis: Neutrophils, Macrophages, Monocytes lyz None lyz:EGFP lyz:DsRed [53]
mpeg1 None mpeg1:EGFP mpeg1:mCherry [54]

rag1 t26683, R797X [55] rag1:GFP [56]
Lymphopoiesis lck None lck:EGFP [57]
ikzf1/ikaros t24980, Q360X [58] ikzf1:GFP [59]