Table 2.
Serum thyroid hormone levels in the LT4 and testmaterials-treatedrats.
| Groups | Serum thyroid hormone concentrations | ||
|---|---|---|---|
| Thyroid stimulating hormone (ng/mL) | Triiodothyronine (ng/mL) | Thyroxine (μg/mL) | |
| Controls | |||
| Intact | 1.57 ± 0.17 | 0.48 ± 0.18 | 39.28 ± 11.97 |
| LT4 | 0.60 ± 0.19a | 1.69 ± 0.20a | 150.40 ± 28.45a |
| Reference | |||
| PTU 10 mg/kg | 1.31 ± 0.17ac | 0.93 ± 0.18ac | 66.88 ± 16.74ac |
| BR treated | |||
| 300 mg/kg | 1.40 ± 0.14bc | 0.74 ± 0.18ac | 59.35 ± 13.34bc |
| 150 mg/kg | 1.30 ± 0.16ac | 0.98 ± 0.10ac | 69.37 ± 11.88ac |
| 75 mg/kg | 1.16 ± 0.12ac | 1.15 ± 0.16ac | 87.19 ± 14.98ac |
Values are expressed mean ± S.D. of eight rats. BR: aqueous Bupleuri Radix extracts; LT4: levothyroxine; PTU: propylthiouracil. a P < 0.01 and b P < 0.05 as compared with intact control by LSD test; c P < 0.01 as compared with LT4 control by LSD test.