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The effect of adenovirus-mediated miR-21 gene transfer on LV dimensions. A, representative heart sections from sham-opened, Ad-GFP, or Ad-miR-21-treated rats at 1 week after I/R. B, Ad-miR-21 (8×108 pfu) reduced internal diastolic diameter of left ventricles in rat hearts at 1 week after I/R. Note: Data presented as mean ± SD, n = 8; *, P< 0.05 compared with Ad-GFP control. † P<0.05 compared with the sham group.
