Table 3.

Risk of All-Cause, Cardiovascular Disease (CVD), and Cancer Mortality per Metabolic Equivalent Increment in Maximal Exercise Test Within Strata of Other Personal Characteristics

Characteristic		All Causes		CVD		Cancer
	Hazard Ratio (95% Confidence Interval) P-Value*
Age
60-69	0.91 (0.88-0.95)	<.001	0.90 (0.85-0.96)	< .001	0.98 (0.90-1.06)	.54
70-79	0.80(0.74-0.88)	< .001	0.78 (0.69-0.89)	< .001	0.88 (0.73-1.06)	.19
≥80	0.57 (0.37-0.90)	.02	0.33 (0.12-0.92)	.03	NA†	NA†
Current smoker
No	0.88(0.85-0.91)	<.001	0.85 (0.80-0.90)	< .001	0.97 (0.90-1.04)	.35
Yes	0.81 (0.72-0.91)	<.001	0.83 (0.70-0.97)	.02	0.69 (0.51-0.92)	.01
Body mass index, kg/m2
18.5-24.9	0.89(0.85-0.93)	< .001	0.89 (0.82-0.95)	.002	0.96 (0.87-1.06)	.42
≥25.0	0.83 (0.79-0.88)	< .001	0.81 (0.75-0.88)	< .001	0.90 (0.81-1.00)	.05
Exercise electrocardiogram responses
Normal	0.87 (0.83-0.91)	< .001	0.82 (0.76-0.89)	< .001	0.95 (0.87-1.03)	.20
Abnormal	0.87(0.82-0.93)	< .001	0.88 (0.81-0.95)	.002	0.93 (0.81-1.06)	.27
Total cholesterol, mmol/L
<6.20	0.84 (0.73-0.98)	.03	0.71 (0.53-0.96)	.03	0.87 (0.64-1.20)	.40
≥6.20	0.88(0.85-0.91)	<.001	0.86(0.81-0.91)	<.001	0.94 (0.87-1.01)	.10
Medical conditions, n‡
0	0.89 (0.84-0.94)	< .001	0.84 (0.76-0.94)	.002	0.97 (0.87-1.08)	.57
1	0.85(0.81-0.90)	<.001	0.83 (0.77-0.89)	< .001	0.90 (0.81-1.00)	.05
≥2	0.89 (0.78-1.00)	.06	0.94 (0.80-1.11)	.45	0.97 (0.74-1.27)	.83
Family history of CVD
No	0.87 (0.84-0.91)	< .001	0.85 (0.80-0.90)	< .001	0.94 (0.87-1.02)	.12
Yes	0.86 (0.76-0.97)	.02	0.85 (0.72-1.01)	.06	0.91 (0.71-1.17)	.48

^*Adjusted for age, sex, examination year, and each of the other variables in the table.

^†NA5not applicable; there were no recorded deaths from cancer among those ≥80.

^‡Number of baseline medical conditions, including diabetes mellitus, cancer, hypertension, stroke, and myocardial infarction.