Figure 2.

The low C:A-fiber ratio in naked mole-rats is largely restricted to cutaneous nerves. A,B: Naked mole-rats have a significantly lower C:A-fiber ratio in cutaneous saphenous and sural nerves compared with all other species. Values for C:A-fiber ratio in common peroneal and tibial nerves (C,D), which innervate both skin and muscle, as well as medial gastrocnemius and lateral gastrocnemius nerves (E,F), which innervate only muscle, are largely similar across all species. Numbers in parentheses refer to the number of ultrathin sections from which average C:A-fiber ratios were calculated. *P < 0.05, **P < 0.01, ***P < 0.001.