Table I.
Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for gastric cancer in relation to the TGFB1 -509C/T and TGFBR2 -875A/G genotypes.
| Genotype | Control (%) | Cases (%) | ORa (95% CI) | P-value |
|---|---|---|---|---|
| TGFB1 -509C/T | ||||
| CT/CC | 536 (69) | 578 (61) | 0.71 (0.58–0.87) | 0.001 |
| CC | 133 (17) | 142 (15) | 0.70 (0.53–0.94) | 0.016 |
| CT | 403 (52) | 436 (46) | 0.72 (0.58–0.89) | 0.002 |
| TT | 245 (31) | 367 (39) | 1 | |
| TGFBR2 -875A/G | ||||
| AG/AA | 305 (39) | 261 (27) | 0.58 (0.62–0.91) | <0.001 |
| AA | 38 (5) | 39 (4) | 0.69 (0.43–1.09) | 0.114 |
| AG | 268 (34) | 222 (23) | 0.56 (0.45–0.70) | <0.001 |
| GG | 478 (61) | 702 (73) | 1 | |
a
Adjusted for age and gender.