Fig. 1.

a Best response by RECIST to hepatic arterial infusion of cisplatin and intravenous doxil in 24 patients evaluable for response. Each red box indicates a patient with maximum response a partial response (≥30% reduction in tumor size) (n = 4), each blue box indicates a patient with stable disease (maximum response between 29% reduction in tumor size to increase by 19% in tumor size) (n = 11) and each black box indicates a patient with progressive disease (≥20% increase in tumor size) (n = 9). b Kaplan–Meier plot for overall survival. c Kaplan–Meier plot for progression-free survival