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. Author manuscript; available in PMC: 2012 Aug 2.
Published in final edited form as: Clin Cancer Res. 2006 Aug 1;12(15):4662–4670. doi: 10.1158/1078-0432.CCR-06-0459

Fig. 5.

Fig. 5

Effects of n-3 diet on PGE2 levels and VEGF mRNA expression in LAPC-4 xenografts. A, PGE2 was extracted from tumors and quantified by high-performance liquid chromatography/diode array detection and electrospray ionization mass spectrometry analysis. PGE2 peak was clearly separated from the PGE3 peak. n = 4 for each group (*, P = 0.01). B, VEGF expression was down-regulated in the n-3 diet group. Total RNA was analyzed for VEGF mRNA relative to GAPDH mRNA using quantitative reverse transcriptase-PCR. n = 8 for n-6 diet and n = 10 for n-3 diet. The experiment was repeated thrice (*, P < 0.05).