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. Author manuscript; available in PMC: 2012 Aug 2.
Published in final edited form as: J Med Virol. 2011 Feb 25;83(5):910–920. doi: 10.1002/jmv.22033

Figure 1.

Figure 1

Schematic overview of the MARSH assay: (A) Eight microarrays contained short oligonucleotides overlapped at half-length that covered the entire genome of the WN/DEN4Δ30 Lot 2 virus. Each microarray contained four identical sub-arrays that were hybridized together. (B) Images of individual sub-arrays hybridized with control and test samples. (C) Ratio of hybridization signals from reference and test sample preparations were plotted to reveal peaks indicating the presence of mutations. The hybridization images and the ratio plot are cartoons given for illustration purposes only.