Vasodilation following local infusion of acetylcholine at increasing dosages (A) and sodium nitroprusside (B) in the brachial artery following the three interventions (vaccine, endotoxin, or saline control). The endotoxin dose resulted in a significant increased resting forearm blood flow compared with saline vaccination (P < 0.05).
Notes: Dosages are in μg/min; means and standard errors of the mean are given; forearm blood flow on the Y axis is given in mL/min/100 mL tissue (n = 12).
Abbreviations: ACh, acetylcholine; FBF, forearm blood flow; SNP, sodium nitroprusside.