Table 1.

The mean cell viabilities (%) after treatment with amiodorane alone and with antioxidant agents

	Cell viability % (Mean ± SD)
Concentration	Amiodarone	Amiodarone + Vitamin Ca	Amiodarone + NACa	p*
20 μM	117.10 ± 50.75	131.31 ± 36.62	133.86 ± 38.91	0.884
40 μM	130.49 ± 48.70	122.12 ± 24.27	91.83 ± 41.86	0.166
60 μM	97.73 ± 48.08	108.25 ± 16.85	133.65 ± 28.12	0.172
80 μM	81.39 ± 64.45	122.00 ± 19.94	120.34 ± 52.70	0.414
100 μM	59.41 ± 16.43	128.43 ± 30.94	108.74 ± 39.04	0.011
120 μM	26.66 ± 7.40	116.63 ± 23.81	74.93 ± 26.31	0.001
140 μM	19.63 ± 6.81	88.11 ± 29.38	80.33 ± 43.47	0.003
160 μM	16.92 ± 6.46	111.55 ± 24.02	70.18 ± 23.15	0.001
180 μM	14.91 ± 4.32	68.52 ± 25.39	48.58 ± 12.21	0.002

^a Vitamin C and NAC were added at one-fold equimolar dose of amiodarone concentrations.

*Kruskal-Wallis test.

NAC: N-acetyl cysteine.