Figure 2. Growth kinetics of wild-type, recombinant and chimeric Ebola viruses during infection in VeroE6 cells.
VeroE6 cells were infected at an MOI = 0.1 with either recombinant REBOV (rREBOV), recombinant ZEBOV (rZEBOV), chimeric REBOV expressing the ZEBOV GP (rREBOV-ZGP), chimeric ZEBOV expressing the REBOV GP (rZEBOV-RGP), parental non-recombinant REBOV (wt-REBOV) or parental non-recombinant ZEBOV (wt-ZEBOV). Samples were collected at 0, 1, 2, 3, 4 and 7 days post-infection and titred based on focus-formation, which was visualized using either an anti-REBOV VP30 serum or an anti-ZEBOV serum. The mean values for each time point along with bars indicating standard error values are shown.