Figure 6. Inhibition of nNOS with L-NPA prevents dilation of arterioles following electrical stimulation.
cPLA2α+/+ slices were equilibrated in 20% O2 and treated with ACSF (hollow square, n = 14; ) or ACSF with 10 µM L-NPA 60 min before electrical stimulation (filled red triangle, n = 9). cPLA2α− /− (filled square, n = 9) were treated with ACSF. Electrical stimulation was applied as indicated by the dark bar (electrical field stimulation, EFS). *, P<.05; **, P<.01.