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. 2012 Aug 2;7(8):e42404. doi: 10.1371/journal.pone.0042404

Figure 3. Fungal homologues of voltage-gated K+ (Kv) channel subunits.

Figure 3

(A) Predicted topology of fungal Kv channel subunit homologues; (B) Multiple sequence alignment of the putative voltage sensor TMD4 regions of human Kv1.2 and fungal Kv channel homologues. Filled triangles above the alignment indicate the positions of conserved basic residues in Kv1.2; (C) Multiple sequence alignment of the putative pore regions of human Kv1.2 and fungal Kv channel homologues. Predicted pore-lining helices of each protein are underlined and the shaded bar indicates the highly conserved GXG motif within the selectivity filter.