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. Author manuscript; available in PMC: 2012 Aug 2.
Published in final edited form as: N Engl J Med. 2009 Oct 8;361(15):1448–1458. doi: 10.1056/NEJMoa0900863

Figure 1. Screening and Random Assignment.

Figure 1

Wb+Mp+ refers to the group that was positive for both Mansonella perstans (Mp) and Wuchereria bancrofti (Wb); Wb−Mp+ refers to the group that was negative for W. bancrofti and positive for M. perstans. Although it was anticipated that 40 subjects would be assigned to each of the subgroups of persons who were negative for W. bancrofti and positive for M. perstans, the initial assignment was made on the basis of the results of an immunochromatographic card test (ICT). Five subjects who had been classified as positive for W. bancrofti on the basis of the ICT were found to be negative for W. bancrofti on the basis of an enzyme-linked immunosorbent assay before the initiation of doxycycline therapy and were reassigned to the corresponding subgroup within the group that was negative for W. bancrofti and positive for M. perstans.