Table 2.

Efficacy of Doxycycline with or without Albendazole–Ivermectin in Reducing Mansonella perstans Microfilarial Levels.

Group	Baseline	6 Months	12 Months	36 Months*
No treatment
No. in group	75	67	63	64
M. perstans (microfilariae/ml)
Median	323	136	153	264
Range	17–20,128	0–5916	0–11,441	0–8305
Doxycycline only
No. in group	76	67	69	64
M. perstans (microfilariae/ml)
Median	357	51	0	0
Range	17–5712	0–1955	0–17	0–383
Doxycycline with albendazole–ivermectin
No. in group	30	26	25	23
M. perstans (microfilariae/ml)
Median	332	51	0	0
Range	17–8313	0–3315	0	0–102
Albendazole–ivermectin only
No. in group	35	31	27	29
M. perstans (microfilariae/ml)
Median	340	102	153	102
Range	17–6120	0–2108	0–799	0–3783

^*All subjects received a single dose of albendazole–ivermectin as part of the mass distribution program before the 36-month visit.