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Effect of Doxycycline on Mansonella perstans wolbachia.
| Group | Detectable M. perstans wolbachia 16S rDNA | |
|---|---|---|
| no. of subjects/no. tested | geometric mean copies/microfilaria (95% CI) | |
| Doxycycline | ||
|
| ||
| Baseline | 45/88 | 2.6 (1.3–5.0) |
|
| ||
| 12 mo | 0/45* | 0 |
|
| ||
| No treatment | ||
|
| ||
| Baseline | 39/94 | 5.97 (3.1–11.4) |
|
| ||
| 12 mo | 39/94 | 7.33 (3.0–18.0) |
Only two subjects had detectable M. perstans microfilariae as assessed by a thick blood smear.
