Table 1.
Baseline characteristics of older adults with Mild Cognitive Impairment.
| Variable | Total MCI N = 3117 |
aMCI n = 2488 |
nonaMCI n = 629 |
p-value |
|---|---|---|---|---|
| Demographic | Mean (SD) | Mean (SD) | Mean (SD) | |
| Age | 74.37 (9.37) | 74.83 (9.33) | 72.57 (9.33) | < .001 |
| Education | 14.91 (3.34) | 14.97 (3.30) | 14.67 (3.45) | .045 |
| Gender M/F (% F) | 1407/1710 (54.9%) | 1132/1356 (54.5%) | 275/354 (56.3%) | .423 |
| Race | ||||
| Caucasian | 2477 (79.5%) | 2017 (81.1 %) | 460 (73.1%) | < .001 |
| African American | 490 (15.7%) | 360 (14.5%) | 130 (20.7%) | |
| Neuropsychological | ||||
| MMSE | 27.27 (2.32) | 27.14 (2.35) | 27.80 (2.13) | < .001 |
| Logical Mem Delayed | 7.04 (4.76) | 6.32 (4.61) | 9.90 (4.21) | < .001 |
| Trailmaking Test A (seconds) | 45.16 (23.48) | 45.13 (23.76) | 45.30 (22.32) | .869 |
| Trailmaking Test B (seconds) | 142.66 (80.34) | 140.41 (78.92) | 151.57 (85.19) | .003 |
| Digit Symbol | 36.90 (12.27) | 37.02 (12.34) | 36.43 (12.01) | .279 |
| CDR Scores | ||||
| CDR sum of boxes | 1.28 (1.13) | 1.33 (1.11) | 1.11 (1.20) | < .001 |
| Median (min/max) | 1.00 (0/9) | 1.00 (0/8) | 0.50 (0/9) | |
| Physical Health | ||||
| % Independent (n) | 77% (2399) | 75.8% (1887) | 81.4% (512) | .003 |
| Hachinski Ischemic Scale | 1.05 (1.46) | 0.99 (1.39) | 1.28 (1.67) | < .001 |
| Psychiatric | ||||
| GDS | 2.49 (2.70) | 2.44 (2.62) | 2.65 (2.98) | .116 |
| GDS ≥ 5, % (n) | 17.3% (538) | 16.6 % (414) | 19.7 % (124) | .068 |
| Function | ||||
| Functional Activities Questionnaire | 3.31 (4.97) | 3.46 (5.04) | 2.71 (4.66) | .002 |
Note. MCI = mild cognitive impairment; aMCI = amnestic MCI; nonaMCI = nonamnestic MCI; MMSE = Mini Mental State Exam; Logical Mem = Logical Memory II (delayed recall); CDR = Clinical Dementia Rating Scale; GDS = Geriatric Depression Scale.