Table 4.
ORs and 95% CIs for combinations of ADRB2 and ADRB3 genetic polymorphisms
Combined genotypes | ||||||
Patients | Control | ORs for breast | Age-adjusted ORs | Mean BMI of control | ||
ADRB2 | ADRB3 | (n) | individuals (n) | cancer (95% CI) | for breast cancer (95% CI) | individuals ± SD |
Gln/Gln | Trp/Trp | 119 | 98 | 1.00 | 1.00 | 22.3 ± 3.0 |
Gln/Gln | /Arg | 56 | 52 | 0.89 (0.56-1.41) | 0.88 (0.55-1.41) | 22.1 ± 2.8 |
/Glu | Trp/Trp | 21 | 23 | 0.75 (0.39-1.44) | 0.76 (0.39-1.46) | 22.4 ± 3.1 |
/Glu | /Arg | 4 | 9 | 0.37 (0.11-1.23) | 0.32 (0.10-1.10) | 22.2 ± 2.9 |
The total number of cases was 200, and that of control individuals was 182. /Arg, a combination of Trp/Arg and Arg/Arg; /Glu, a combination of Gln/Glu and Glu/Glu.