TABLE 1.

Differences between PrkD and PrkG

Characteristic	PrkD	PrkG
Expression analysis	All phases, maximum in late log phase, less than PrkG except in stationary phase	All phases, maximum in mid- and late-log phases
Hanks subdomains	10	7
Activation loop	Present, RD kinase	Absent, non-RD kinase
Dual specificity/class	Yes/DYRK	Yes/DSPK
Autophosphorylation	Ser/Thr/Tyr	Ser/Thr/Tyr
Transphosphorylation	Ser/Thr	Ser/Thr/Tyr
Involvement of Tyr	Autophosphorylation and substrate phosphorylation	Autophosphorylation
Conservation	Throughout Bacillus species	Only in pathogenic B. cereus group
Rossmann fold	Present	Irregular
Substrate phosphorylation
MyBP	Yes	Yes
BasPyk	Yes	No