Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Nef and Kir2.3 share a common binding site in AP-2. A, mutation of a key residue in the di-Leu-binding pocket of AP-2 (σ2L103S) prevented binding to Nef and significantly decreased binding to Kir2.3. Shown are representative Western blots. IB, immunoblot. B, densitometric quantification and summary of the data from three separate experiments (mean ± S.E.; *, p < 0.05).
