TABLE 1.
The top 40 genes ranked by fold change identified as being up-regulated in T-cells following LFA-1/ICAM-1 interaction
| Probe ID | Symbol | Gene name | Fold change |
|---|---|---|---|
| 44783_s_at | HEY1 | Hairy/enhancer-of-split related with YRPW motif 1 | 56.82 |
| 222450_at | TMEPAI | Transmembrane, prostate, androgen-induced RNA | 48.92 |
| 217591_at | SKIL | SKI-like | 15.48 |
| 240156_at | RFX2 | Regulatory factor X, 2 | 13.84 |
| 235497_at | LOC643837 | Hypothetical protein LOC643837 | 13.55 |
| 229613_at | NKD1 | Naked cuticle 1 homolog (Drosophila) | 13.4 |
| 213506_at | F2RL1 | Coagulation factor II (thrombin) receptor-like 1 | 12.52 |
| 230820_at | SMURF2 | SMAD-specific E3 ubiquitin protein ligase 2 | 9.832 |
| 209574_s_at | C18orf1 | Chromosome 18 open reading frame 1 | 9.73 |
| 1560676_at | SIAH3 | Seven in absentia homolog 3 | 9.293 |
| 1556423_at | VASH1 | Vasohibin 1 | 9.273 |
| 212907_at | SLC30A1 | Solute carrier family 30 (zinc transporter), member 1 | 9.234 |
| 216297_at | BBIP1 | BBSome interacting protein 1 | 7.938 |
| 218793_s_at | SCML1 | Sex comb on mid leg-like protein 1 | 7.832 |
| 232081_at | ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 7.69 |
| 212666_at | SMURF1 | SMAD-specific E3 ubiquitin protein ligase 1 | 6.71 |
| 209324_s_at | RGS16 | Regulator of G-protein signalling 16 | 6.355 |
| 204270_at | SKI | v-SKI sarcoma viral oncogene homolog (avian) | 6.186 |
| 204995_at | CDK5R1 | Cyclin-dependent kinase 5, regulatory subunit1 (p35) | 6.128 |
| 204790_at | SMAD7 | SMAD family member 7 | 5.911 |
| 225142_at | JHDM1D | Jumonji C domain containing histone demethylase 1 | 5.656 |
| 205977_s_at | EPHA1 | EPH receptor A1 | 5.258 |
| 212680_x_at | PPP1R14B | Protein phosphatase 1, regulatory (inhibitor) subunit 14B | 5.179 |
| 228067_at | C2orf55 | Chromosome 2 open reading frame 55 | 5.112 |
| 205016_at | TGFA | Transforming growth factor, α | 4.895 |
| 235851_s_at | GNAS | GNAS complex locus | 4.89 |
| 213629_x_at | MT1F | Metallothionein 1F (functional) | 4.877 |
| 220009_at | LONRF3 | LON peptidase N-terminal domain and ring finger 3 | 4.7 |
| 225481_at | FRMD6 | FERM domain containing 6 | 4.66 |
| 213060_s_at | CHI3L2 | Chitinase 3-like 2 | 4.64 |
| 216268_s_at | JAG1 | Jagged 1 | 4.51 |
| 1565525_a_at | TCP11L2 | t-Complex 11 (mouse)-like 2 | 4.464 |
| 213994_s_at | SPON1 | Spondin 1, extracellular matrix protein | 4.34 |
| 201389_at | ITGA5 | Integrin, α5 | 4.316 |
| 236241_at | MED31 | Mediator of RNA polymerase II transcription, subunit 31 | 4.225 |
| 203066_at | CHST15 | Carbohydrate sulfotransferase 15 | 4.199 |
| 223916_s_at | BCOR | BCL6 co-repressor | 4.141 |
| 231798_at | NOG | Noggin | 4.055 |
| 205899_at | CCNA1 | Cyclin A1 | 4.01 |
| 212582_at | OSBPL8 | Oxysterol binding protein-like 8 | 4 |