TABLE 2.
The top 40 genes ranked by fold change identified as being down-regulated in T-cells following LFA-1/ICAM-1 interaction
| Probe ID | Symbol | Gene name | Fold change |
|---|---|---|---|
| 205898_at | CX3CR1 | Chemokine (C-X3-C motif) receptor 1 | −17.92 |
| 1553681_a_at | PRF1 | Perforin1 (pore-forming protein) | −8.06 |
| 207651_at | GPR171 | G protein-coupled receptor 171 | −5.92 |
| 209840_s_at | LRRN3 | Leucine-rich repeat neuronal 3 | −5.81 |
| 1565566_a_at | STX7 | Syntaxin 7 | −5.41 |
| 207324_s_at | DSC1 | Desmocollin 1 | −5.03 |
| 207583_at | ABCD2 | ATP-binding cassette, subfamily D (ALD), member 2 | −4.93 |
| 206364_at | KIF14 | Kinesin family member 14 | −4.85 |
| 1569107_s_at | ZNF642 | Zinc finger protein 642 | −4.67 |
| 236226_at | BTLA | B and T lymphocyte-associated | −4.55 |
| 224414_s_at | CARD6 | Caspase recruitment domain family, member 6 | −4.48 |
| 202870_s_at | CDC20 | CDC20 cell division cycle 20 | −4.46 |
| 228057_at | DDIT4L | DNA damage-inducible transcript 4-like | −4.41 |
| 215894_at | PTGDR | Prostaglandin D2 receptor | −4.35 |
| 209773_s_at | RRM2 | Ribonucleotide reductase M2 polypeptide | −4.22 |
| 207761_s_at | METTL7A | Methyltransferase-like 7A | −4.18 |
| 244654_at | MYO1G | Myosin IG | −4.18 |
| 238581_at | GBP5 | Guanylate-binding protein 5 | −4.10 |
| 205467_at | CASP10 | Caspase-10, apoptosis-related cysteine peptidase | −4.08 |
| 202589_at | TYMS | Thymidylate synthetase | −4.00 |
| 218663_at | NCAP-G | Non-SMC condensin I complex, subunit G | −3.95 |
| 209714_s_at | CDKN3 | Cyclin-dependent kinase inhibitor 3 | −3.94 |
| 232375_at | STAT1 | Signal transducer and activator of transcription 1 | −3.70 |
| 201291_s_at | TOP2A | Topoisomerase (DNA) II α 170 kDa | −3.69 |
| 1563209_a_at | C20orf133 | Chromosome 20 open reading frame 133 | −3.57 |
| 226661_at | CDCA2 | Cell division cycle associated 2 | −3.55 |
| 208059_at | CCR8 | Chemokine (C-C motif) receptor 8 | −3.42 |
| 221969_at | PAX5 | Paired box gene5 (B-cell lineage-specific activator) | −3.41 |
| 224160_s_at | ACAD9 | Acyl-coenzyme A dehydrogenase family, member 9 | −3.33 |
| 202458_at | PRSS23 | Protease, serine, 23 | −3.29 |
| 228055_at | NAPSB | Napsin B aspartic peptidase | −3.27 |
| 219787_s_at | ECT2 | Epithelial cell transforming sequence 2 oncogene | −3.25 |
| 202269_x_at | GBP1 | Guanylate binding protein 1 | −3.11 |
| 215358_x_at | ZNF37B | Zinc finger protein 37b (KOX 21) | −3.11 |
| 205297_s_at | CD79B | CD79B antigen (immunoglobulin-associated β) | −2.81 |
| 220118_at | ZBTB32 | Zinc finger and BTB domain containing 32 | −2.77 |
| 235372_at | FCRLA | Fc receptor-like A | −2.75 |
| 226453_at | AYP1 | AYP1 protein | −2.7 |
| 226453_at | RNASEH2C | Ribonuclease H2, subunit C | −2.67 |
| 202531_at | IRF1 | Interferon regulatory factor 1 | −2.62 |