Figure 1.
Activity profiles for global TFs predicted from gene expression datasets. (a) Inferred activities of the indicated global TFs in stable steady-state cultures grown at defined points on the aerobiosis scale. (b) Inferred activities of the global TFs in the unstable environments of transitions from anaerobic to aerobic conditions (diamonds, solid lines) and aerobic to anaerobic conditions (squares, dashed lines). The inferred activities arise from the term cm(t) in the TFInfer model [11]. In all cases, the signal-to-noise ratio was more than 5.