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. 2012 Apr-Jun;4(2):87–97.

Table 1.

Toxicity indices of the selected compounds – thiohydrazones of thiohydrazides of oxamine acids


Compound № Structure Methylene blue staining, % of dead cells Calcein assay, 
% of dead cells MTT assay, 
% of metabolically 
inactive cells
12.5
µM 25
µM 50
µM 12.5
µM 25
µM 50
µM 12.5 µM 25
µM 50
µM
1 graphic file with name AN20758251-13-087-f001.jpg 0+2 12+2 23+2 0+2 11+2 20+2 3+1 12+3 29+3
2 graphic file with name AN20758251-13-087-f002.jpg 2+2 13+1 24+3 3+2 12+1 21+3 3+2 15+1 31+5
3 graphic file with name AN20758251-13-087-f003.jpg 6+4 20+2 27+2 5+4 16+2 23+2 2+2 15+5 30+4
4 graphic file with name AN20758251-13-087-f004.jpg 5+1 15+2 28+2 6+1 12+2 23+2 3+3 13+4 28+2
5 graphic file with name AN20758251-13-087-f005.jpg 2+1 14+2 26+3 3+1 16+2 22+3 4+3 20+4 29+6
6 graphic file with name AN20758251-13-087-f006.jpg 2+1 15+2 26+2 5+1 12+2 24+2 2+4 17+5 27+8
7 graphic file with name AN20758251-13-087-f007.jpg 2+2 15+4 29+5 4+2 16+4 22+5 4+5 18+3 29+9
8 graphic file with name AN20758251-13-087-f008.jpg 2+1 14+1 24+4 6+1 12+1 24+4 3+3 15+3 28+4
9 graphic file with name AN20758251-13-087-f009.jpg 2+1 12+1 24+4 4+1 15+1 25+4 4+5 20+4 30+4
10 graphic file with name AN20758251-13-087-f010.jpg 2+1 12+2 24+2 5+1 14+2 22+2 3+3 19+3 31+7
11 graphic file with name AN20758251-13-087-f011.jpg 1+1 12+1 21+4 4+1 13+1 25+4 5+1 16+2 30+5
12 graphic file with name AN20758251-13-087-f012.jpg 0+1 11+1 22+3 3+1 10+1 24+3 5+5 15+4 29+6
13 graphic file with name AN20758251-13-087-f013.jpg 2+1 15+2 26+3 2+1 11+2 25+3 5+4 14+3 29+7
14 graphic file with name AN20758251-13-087-f014.jpg 4+1 15+1 25+4 3+1 12+1 22+4 3+5 17+3 28+6
15 graphic file with name AN20758251-13-087-f015.jpg 0+1 11+2 22+3 0+1 10+2 21+3 4+1 13+3 29+5