Figure 3.

Dynamic properties of two-kinesin complexes in the model where local interactions affect only motor-filament affinities. A. Detachment and binding rates: experimentally measured detachment rates are shown by circles, while blue and black curves correspond to calculated values of detachment and binding rates, respectively. B. Distribution of two-motor load-sharing and single-motor bound states as a function of the load. The blue and red triangles represent experimentally measured fractions of load-sharing and single motor states, respectively. Calculated two-motor load sharing and non-load sharing states are shown in blue and red, respectively. C. Force-velocity relationships under static-trap conditions. Symbols correspond to experimental measurements. Black and blue curves describe calculated values for original configurational energies and for modified by interactions configurational energies (see text for details), respectively. D. Force-velocity relationships for force-clamp conditions. Symbols correspond to experimental measurements. Black and blue curves describe calculated values for original configurational energies and for modified configurational energies (see text for details), respectively.