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Effect of monosodium urate on macrophage DNA synthesis
| Addition | [3H]TdR incorporation (cpm × 10-4) |
| None | 1.6 ± 0.1 |
| MSU | 13.5 ± 0.5 |
| BCP | 24.3 ± 0.3 |
BMMs from which CSF-1 had just been removed were cultured in RPMI/10%FBS, in the absence or presence of monosodium urate (MSU) (500 μg/ml) or BCP (500 μg/ml). After one day, cells were pulsed with [3H]TdR for a further two days. Data are mean values ± SEM from triplicate cultures and are from a representative experiment that was repeated twice.
