Fig. 6. Effect of recombinant IFN-λ on HSV-1 infection.
Human primary astrocytes were treated with recombinant human IFN-λ1 or IFN-λ2 (100ng/ml) for 24h and then infected with HSV-1 (MOI 0.01). Supernatant from the cultures was collected at indicated time points postinfection and subjected to DNA extraction. Extracellular HSV-1 gD gene expression was examined by using serial dilutions of HSV-1 gD standards with known copy number. All value is the mean ± SD of three independent experiments.