TABLE 1.
Demographics and baseline values of lung function in children with and without asthma
| Parameter | Stable asthma | Controls | 95% CI | P |
|---|---|---|---|---|
| Age, years | 4.6±0.4 | 4.6±0.3 | 0.732 | |
| Sex, (male/female), n/n | 14/16 | 14/15 | 0.616 | |
| Height, cm | 110.6±9.8 | 108.7±5.9 | 0.371 | |
| Weight, kg | 19.9±4.6 | 18.4±3.3 | 0.160 | |
| Spirometry | ||||
| FEV1, L | 1.0±0.3 | 1.0±0.2 | −0.13 to 0.17 | 0.775 |
| FEV1, % predicted | 102.3±26.2 | 96.2±14.4 | −0.18 to 0.05 | 0.269 |
| FVC, L | 1.1±0.4 | 1.1±0.3 | −0.20 to 0.14 | 0.704 |
| FVC, % predicted | 119.1±32.0 | 111.5±17.3 | −0.21 to 0.06 | 0.263 |
| FEV1/FVC, % | 89.9±6.5 | 93.7±4.0 | 1.00 to 6.63 | 0.009 |
| FEF25–75/FVC, % | 102.0±23.1 | 135.6±33.5 | 18.7 to 48.6 | <0.001 |
| Impulse oscillation system | ||||
| Rrs5, kPa s L−1 | 1.10±0.30 | 0.99±0.21 | −0.238 to 0.030 | 0.126 |
| Rrs5, % predicted | 88.3±20.3 | 90.1±16.0 | −0.08 to 0.11 | 0.711 |
| Xrs5, kPa s L−1 | −0.42±0.18 | −0.34±0.13 | 0.001 to 0.169 | 0.046 |
| Xrs5, % predicted | −34.4±8.3 | −35.5±5.5 | −0.05 to 0.03 | 0.532 |
Data presented as mean ± SD unless otherwise indicated. Spirometric measurements (forced expiratory volume in 1 s [FEV1], forced expiratory flow at 25% to 75% [FEF25–75] of forced vital capacity [FVC], and FVC) are presented as per cent predicted or initial values. Comparisons attaining a level of significance of at least 0.05 are indicated in bold. IOS measurements are expressed as resistance and reactance at 5 Hz FEF25–75. Rrs5 Respiratory resistance at 5 Hz; Xrs5 Respiratory reactance at 5 Hz