Table 2.
Characteristics of cohort studies of hepatitis viruses infection and ICC risk
| First author | Year | Country | Source | Sample size |
Mean follow-up (years) |
ICC | Hazard ratio 95% CI |
Study , quality |
|---|---|---|---|---|---|---|---|---|
| Tanaka |
2009 |
Japan |
Voluntary blood donors |
2519 (HBsAg +) |
7.6 |
2 |
8.56 (1.33-55.2) |
3 |
| 1927 (anti-HCV+) |
1 |
2.63 (.25-27.73) |
||||||
| 150368 (all negative) |
8 |
|
||||||
| El-Serag |
2009 |
US |
Veterans population |
146394 (anti-HCV+) |
2.3 |
14 |
2.6 (1.3-5.0) |
2 |
| 572293 (anti-HCV–) |
23 |
|||||||
| Fwu | 2011 | Taiwan | Pregnant women | 289992 (HBsAg +) |
6.91 | 9 |
4.80 (1.88-12.2) | 2 |
| 1492409 (HBsAg –) | 9 |
ICC, intrahepatic cholangiocarcinoma; HBsAg, hepatitis B surface antigen; HCV, hepatitis C virus; US, United States.