Figure 3. A CD47^low status is linked to TSP-1-induced cell death susceptibility.

(A–B) Specific CD47-mediated killing was performed using 4N1K (TSP-1) or 4NGG (control) peptide on in vitro restimulated FACS sorted activated CD47^low T cells as in Figure 2 (A) and ex vivo isolated CD4 T cell subsets (B). (A–B) The mean ± standard deviation (SD) for 5 independent experiments. Student t test: *p<0.05, ***p<0.0001. (C) Calreticulin expression is shown after specific CD47-mediated killing as in B. Data are representative of 4 independent experiments.