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. 2012 Aug 1;7(8):e41972. doi: 10.1371/journal.pone.0041972

Figure 5. CD47 on CD4 T cells regulates the contraction of the immune response in vivo.

Figure 5

One day after adoptive transfer of CD47+/+ or CD47−/− Tg T cells isolated from DO11.10 mice into CD47−/− BALB/c hosts, mice were immunized s.c. with CFA-OVA or DEC205-OVA. (A and C) Kinetic of the recovery of viable Tg T cells is shown. (B) CD47 status (SIRP-α-Fc protein) gated on CD4 KJ126+(Tg) T cells post immunization. Data are representative of 4 to 6 independent experiments, student t test was performed on 8 to 12 mice. *p<0.05, ***p<0.001.