Figure 6. Analysis of DNA lesions in TcOGG1-overexpressor T. cruzi.

Ratio between nuclear and mitochondrial DNA lesions from TcOGG1-overexpressing cells in comparison to control cells, after treatment with 200 µM H₂O₂. Both cell populations were treated for 20 min and allowed to recover for up to 24 hours. Data are expressed as the mean of two biological experiments. Error bars represent standard error of the mean. Statistical analysis used was unpaired t test. ** - P value<0,01; * - P value<0,1.