Table 5. Plasma insulin, adiponectin, leptin, TG and cholesterol levels at the end of treatment.
Treatment | Insulin (ng/mL) | AdipQ (µg/mL) | Leptin (ng/mL) | TG (mg/dL) | Total cholesterol (mg/dL) |
Lean | 0.51±0.08* | 24.0±1.3 | 7.21±0.51* | 273±15* | 92±2* |
DIO Veh | 2.92±0.46 | 21.2±0.9 | 32.47±1.20 | 178±9 | 158±4 |
CB1 ASO 25 mg/kg/wk | 0.69±0.09* | 25.9±1.1* | 21.95±1.88* | 189±18 | 111±4* |
CB1 ASO 12.5 mg/kg/wk | 1.73±0.35 | 23.9±1.1 | 30.73±1.34 | 196±13 | 141±5* |
CB1 ASO 6.25 mg/kg/wk | 2.04±0.38 | 21.4±1.0 | 30.93±1.73 | 193±21 | 147±6 |
Control ASO 25 mg/kg/wk | 2.13±0.45 | 25.5±0.4* | 32.80±1.11 | 195±16 | 170±4 |
Values shown are mean ± se. One way ANOVA Dunnett’s multiple test compared to DIO Veh, *p<0.05.