Table 8. Plasma creatinine, BUN, lipase, ALT and AST levels at the end of treatment.

Treatment	Creatinine (mg/dL)	BUN (mg/dL)	Lipase (U/L)	ALT (U/L)	AST (U/L)
Lean Veh	0.32±0.01	18.5±0.7	76±12	54±14*	64±6*
DIO Veh	0.35±0.01	16.1±0.9	86±2	125±11	106±12
CB1 ASO 25 mg/kg/wk	0.33±0.00	14.9±0.9	70±4	80±6*	103±12
CB1 ASO 12.5 mg/kg/wk	0.36±0.02	17.5±1.5	89±5	122±10	138±32
CB1 ASO 6.25 mg/kg/wk	0.33±0.01	15.9±0.3	97±10	103±15	85±9
Control ASO 25 mg/kg/wk	0.47±0.13	17.1±0.3	90±2	73±7*	71±5*

Values shown are mean ± se. One way ANOVA Dunnett’s multiple test compared to DIO Veh, *p<0.05.