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. 2012 Aug 3;7(8):e42310. doi: 10.1371/journal.pone.0042310

Figure 7. CTO inhibits the effects of LAMA84R exosomes on HUVEC migration.

Figure 7

(a) Effects on migration of CTO-treated endothelial cells using 50 µg/ml of exosomes as chemoattractant. (b) 50 µg/ml of exosomes (Exo) with or without 10 µg/ml of neutralizing anti-IL8 antibody (N Ab IL8), or 10 ng/ml of recombinant IL8 (Rec IL8) with or without neutralizing anti-IL8 antibody were added as chemoattractants to the bottom wells., Motility of endothelial cells with or without increasing doses of CTO (1–10 µM) was evaluated as described in Material and Methods. *p≤0.05; **p≤0.01.