Figure 2. Basal cardiovascular 24 hour cardiovascular profile in sham-operated and uni-x female sheep at 1 year, 2 and 5 years of age.

(A) Mean arterial pressure, MAP (B) cardiac output, CO (C) Total peripheral resistance, TPR, (D) Heart rate, (E) Stroke volume, SV and (F) blood volume. Values are from two-way repeated ANOVA and expressed as mean ± SEM. Sham (n = 5); clear bars, uni-x (n = 5); dark bars. *P<0.05, **P<0.01, ***P<0.001 as compared to sham group from post-hoc analysis.