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. 2012 Aug 3;7(8):e42529. doi: 10.1371/journal.pone.0042529

Figure 4. Overall structural changes of gut microbiota.

Figure 4

(A) PCoA score plot based on unweighted UniFrac metrics. Each point represents the mean principal component scores of all rats in a group at one time point, and the error bar represents the standard deviation. (B) Clustering of gut microbiota based on mahalanobis distances calculated using MANOVA, * P<0.05. (C) Shannon-Wiener index, calculated after rarefying to an equal number of sequence reads for all samples. Values are expressed as means ± standard error. * P<0.05, significant difference when compared with the 0th week value as assessed by ANOVA.