Table 2. Top 10 fold-changing genes from each expression cluster.
| Cluster ID | Gene Symbol | Gene Description | Fold Change* |
| Cluster 1 | MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase | 67.97 |
| PDLIM1 | PDZ and LIM domain 1 | 52.51 | |
| TKDP3 | Trophoblast Kunitz domain protein 3 | 51.70 | |
| MYH3 | Myosin heavy chain 3 | 45.83 | |
| WWC1 | WW, C2 and coiled domain containing 1 | 31.36 | |
| C4orf19 | Chromosome 4 open reading frame 19 | 29.70 | |
| CEBPE | CCAAT/enhancer binding protein (C/EBP) epsilon | 23.09 | |
| TRPC6 | Transient receptor potential cation channel, subfamily C, member 6 | 22.49 | |
| EMR4P | EGF-like module containing, mucin-like, hormone receptor-like 4 | 22.35 | |
| HOXB6 | Homeobox B6 | 22.29 | |
| Cluster 2 | COBRA1 | Co-factor of BRCA1 | 5.67 |
| KIAA0649 | KIAA0649 | 3.72 | |
| MAPK7 | Mitogen-activated protein kinase 7 | 3.67 | |
| MYH1 | Myosin heavy chain 1 | 3.64 | |
| KCNQ1 | Potassium voltage-gated channel, KQT-like subfamily, member 1 | 3.42 | |
| FHL3 | Four and a half LIM domains 3 | 3.12 | |
| CTTN | Cortactin | 3.11 | |
| PNKD | Paroxysmal nonkinesiogenic dyskinesia | 3.07 | |
| MYH4 | Myosin heavy chain 4 | 2.96 | |
| RAB26 | RAB26, member RAS oncogene family | 2.92 | |
| Cluster 3 | N/A | N/A | −5.12 |
| LDLRAD3 | Low density lipoprotein receptor class A domain containing 3 | −4.24 | |
| N/A | N/A | −4.08 | |
| AXL | AXL receptor tyrosine kinase | −3.55 | |
| CSNK1G3 | Casein kinase 1, gamma 3 | −3.14 | |
| N/A | N/A | −3.05 | |
| C4orf16 | Chromosone 4 open reading frame 16 | −3.05 | |
| ACSL3 | Acyl-CoA synthetase long chain family member 3 | −3.04 | |
| KBTBD4 | Kelch repeat and BTB (POZ) domain containing 4 | −2.86 | |
| HOOK1 | Hook homolog 1 | −2.83 | |
| Cluster 4 | ALAS2 | Aminolevulinate, delta-, synthase 2 | −59.17 |
| AQP1 | Aquaporin 1 | −25.83 | |
| SYNJ2 | Synaptojanin 2 | −22.46 | |
| MAL | Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein) | −20.54 | |
| ZSWIM4 | Zinc finger, SWIM-type containing 4 | −15.74 | |
| CYP4F12 | Cytochrome P450, family 4, subfamily F, polypeptide 12 | −14.75 | |
| SLC22A1 | Solute carrier family 22 (organic cation transporter) member 1 | −13.56 | |
| N/A | N/A | −12.05 | |
| N/A | N/A | −8.33 | |
| OR2S2 | Olfactory receptor, family 2, subfamily S, member 2 | −7.84 | |
| Cluster 5 | SPP1 | Secreted phosphoprotein 1 | 53.34 |
| PTX3 | Pentraxin-related gene, rapidly induced by IL1-beta | 8.24 | |
| ANXA9 | Annexin A9 | 6.58 | |
| S100A9 | S100 calcium binding protein A9 | 6.45 | |
| S100A8 | S100 calcium binding protein A8 | 6.27 | |
| ECM1 | Extracellular matrix protein 1 | 6.26 | |
| IL1R2 | Interleukin 1 receptor, type II | 5.55 | |
| KLHL4 | Kelch-like 4 | 5.21 | |
| LOC255649 | Oocyte-secreted protein variant 1 | 5.09 | |
| CDH4 | Cadherin 4, type 1, R-cadherin (retinal) | 4.12 | |
| Cluster 6 | ZBTB41 | Zinc finger and BTB domain containing 41 | −4.59 |
| GBP3 | Guanylate binding protein 3 | −4.53 | |
| C20orf194 | Chromosome 20 open reading frame 194 | −3.79 | |
| MTRR | 5-methyltetrahydrofolate-homocyst cysteine methyltransferase reductase | −3.29 | |
| DMXL2 | DMX-like 2 | −2.68 | |
| SF3B4 | Splicing factor 3b, subunit 4 | −2.53 | |
| OSR2 | Odd-skipped related 2 | −2.32 | |
| YAF2 | YY1 associated factor 2 | −2.29 | |
| DEPDC7 | DEP domain containing 7 | −2.06 |
*
Fold change calculated based on the peak fold change (compared to baseline, time = 0) for each gene across the time course of infestation with P. ovis.