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FS patients have high levels of anti-SGLL IgG4 and IgE antibodies. (A). Boxplot analysis of the IgG4 and IgE responses in FS patients (n=45) and UNC healthy controls (n=43) against SGLL antigens by ELISA. The index values are higher in the FS group than the HC-UNC group. (B). Pearson correlation analysis between the IgG4 anti-SGLL and the IgG4 anti-Dsg1 responses (upper panel) and the IgE anti-SGLL and IgG4 anti-SGLL responses (lower panel) in the same donors of the FS group.
