Table IV.
HLA restriction of prevalently recognized epitope regions
| Region restriction(s) |
|||||||
|---|---|---|---|---|---|---|---|
| Organism | Source | Donors responding | % responding | Total SFC | DR | DQ | DP |
| Alt. Rot Fungus | Alt a 1 (6-25) | 4 | 33.3 | 5572 | 4 | 0 | 0 |
| Alt a 1 (116-135) | 7 | 58.3 | 7450 | 3 | 3 | 0 | |
| Alt a 1 (141-157) | 5 | 41.7 | 5768 | 5 | 0 | 0 | |
| Alt a 5 (51-65) | 2 | 16.7 | 3450 | 1 | 0 | 0 | |
| Alt a 6 (161-175) | 2 | 16.7 | 1238 | 0 | 0 | 1 | |
| Alt a 7 (6-20) | 2 | 16.7 | 727 | 1 | 0 | 0 | |
| Alt a 7 (190-204) | 2 | 16.7 | 397 | 0 | 0 | 0 | |
| A. fumigatus | Asp f 17 (91-105) | 2 | 18.2 | 813 | 1 | 0 | 0 |
| C. herbarum | Cla h 5 (6-20) | 2 | 20.0 | 247 | 0 | 0 | 0 |
| Cla h 6 (161-175) | 3 | 30.0 | 2082 | 1 | 0 | 1 | |
| Cla h 8 (101-115) | 2 | 20.0 | 317 | 0 | 0 | 0 | |
| Cla h 8 (151-165) | 2 | 20.0 | 470 | 1 | 0 | 0 | |
| Cla h 8 (181-195) | 2 | 20.0 | 817 | 0 | 0 | 0 | |
| Cla h 8 (236-250) | 2 | 20.0 | 4067 | 1 | 1 | 0 | |
| P. chrysogenum | Pen ch 13 (101-115) | 2 | 20.0 | 677 | 1 | 0 | 0 |
| Pen ch 13 (271-285) | 2 | 20.0 | 1463 | 1 | 0 | 0 | |
| Pen ch 18 (226-240) | 2 | 20.0 | 607 | 1 | 0 | 0 | |
| Pen ch 18 (291-305) | 3 | 30.0 | 2480 | 2 | 0 | 0 | |
| Cat epithelia | Fel d 1 (41-60) | 3 | 27.3 | 6065 | 3 | 0 | 0 |
| Fel d 1 (78-92) | 3 | 27.3 | 3453 | 3 | 0 | 0 | |
| Fel d 1 (21-40) | 6 | 54.5 | 7128 | 2 | 0 | 2 | |
| Fel d 1 (36-50) | 2 | 18.2 | 2837 | 1 | 0 | 0 | |
| D. farinae | Der f 1 (131-150) | 2 | 20.0 | 1448 | 2 | 0 | 0 |
| D. pteronyssinus | Der p 1 (131-150) | 2 | 18.2 | 2417 | 2 | 1 | 0 |
| Der p 1 (176-190) | 2 | 18.2 | 890 | 2 | 0 | 0 | |
| Der p 1 (226-240) | 2 | 18.2 | 2783 | 1 | 1 | 0 | |
| Der p 4 (96-120) | 3 | 27.3 | 3877 | 2 | 0 | 0 | |
| Der p 4 (251-265) | 2 | 18.2 | 763 | 0 | 0 | 1 | |
| Der p 4 (321-335) | 2 | 18.2 | 1570 | 0 | 1 | 0 | |
| Der p 4 (381-400) | 4 | 36.4 | 2573 | 2 | 0 | 0 | |
| Der p 4 (411-430) | 2 | 18.2 | 1117 | 0 | 0 | 1 | |
| Der p 4 (482-502) | 2 | 18.2 | 1160 | 1 | 0 | 0 | |
| Alder | Aln g 1 (11-30) | 2 | 16.7 | 2036 | 0 | 1 | 1 |
| Aln g 1 (111-125) | 2 | 16.7 | 1244 | 1 | 1 | 0 | |
| Birch | Bet v 1 (96-110) | 2 | 20.0 | 462 | 0 | 0 | 0 |
| Bet v 1 (111-125) | 3 | 30.0 | 1132 | 2 | 0 | 0 | |
| Bet v 6 (211-230) | 2 | 20.0 | 807 | 0 | 1 | 0 | |
| Cypress | Cha o 1 (86-110) | 3 | 30.0 | 1922 | 1 | 0 | 0 |
| Cha o 1 (211-225) | 2 | 20.0 | 835 | 0 | 0 | 0 | |
| Cup a 1 (71-90) | 3 | 30.0 | 3067 | 1 | 0 | 0 | |
| Cup a 1 (316-330) | 3 | 30.0 | 740 | 1 | 1 | 0 | |
| Cup s 1 (91-115) | 3 | 30.0 | 3627 | 1 | 0 | 0 | |
| Cup s 1 (211-225) | 2 | 20.0 | 1650 | 1 | 0 | 0 | |
| White Oak | Que a 1 (11-35) | 8 | 61.5 | 7183 | 1 | 0 | 3 |
| Que a 1 (141-155) | 4 | 30.8 | 1337 | 1 | 0 | 1 | |
| Orchard Grass | Dac g 1 (181-195) | 4 | 36.4 | 2795 | 2 | 0 | 0 |
| Dac g 2 (11-30) | 2 | 18.2 | 1917 | 1 | 0 | 0 | |
| Dac g 4 (1-15) | 3 | 27.3 | 482 | 0 | 0 | 0 | |
| Rye Grass | Lol p 1 (176-190) | 3 | 27.3 | 1180 | 1 | 0 | 0 |
| Lol p 2 (51-70) | 4 | 36.4 | 1163 | 3 | 0 | 0 | |
| Lol p 2 (76-90) | 3 | 27.3 | 1253 | 0 | 2 | 0 | |
| Lol p 3 (11-25) | 3 | 27.3 | 2070 | 2 | 0 | 0 | |
| Lol p 3 (51-65) | 2 | 18.2 | 1803 | 1 | 0 | 0 | |
| Lol p 3 (76-90) | 2 | 18.2 | 3342 | 0 | 0 | 0 | |
| Lol p 5 (71-85) | 3 | 27.3 | 3325 | 0 | 2 | 1 | |
| Lol p 5 (156-175) | 3 | 27.3 | 3437 | 0 | 2 | 0 | |
| Lol p 5 (236-250) | 2 | 18.2 | 460 | 0 | 0 | 0 | |
| Lol p 5 (306-320) | 2 | 18.2 | 1695 | 0 | 1 | 0 | |
| Lol p 5 (181-195) | 3 | 27.3 | 2260 | 1 | 1 | 1 | |
| Lol p 11 (116-135) | 2 | 18.2 | 2393 | 0 | 0 | 1 | |
| Canary Grass | Pha a 1 (186-200) | 4 | 40.0 | 2095 | 3 | 1 | 0 |
| Pha a 5 (121-140) | 3 | 30.0 | 1680 | 1 | 1 | 0 | |
| Pha a 5 (166-180) | 2 | 20.0 | 2222 | 0 | 1 | 1 | |
| Pha a 5 (181-195) | 2 | 20.0 | 493 | 2 | 0 | 0 | |
| Pha a 5 (201-220) | 4 | 40.0 | 1502 | 3 | 1 | 0 | |
| Ken. Blue Grass | Poa p 1 (121-135) | 3 | 25.0 | 1357 | 1 | 0 | 0 |
| Poa p 5 (51-75) | 7 | 58.3 | 3528 | 0 | 1 | 1 | |
| Poa p 5 (121-135) | 3 | 25.0 | 435 | 1 | 0 | 0 | |
| Poa p 5 (131-145) | 2 | 16.7 | 243 | 1 | 0 | 0 | |
| Poa p 5 (176-190) | 6 | 50.0 | 1862 | 3 | 0 | 1 | |
| Poa p 5 (211-230) | 4 | 33.3 | 1738 | 3 | 0 | 0 | |
| Poa p 5 (221-235) | 2 | 16.7 | 1370 | 1 | 0 | 0 | |
| Russian Thistle | Sal k 1 1 (191-205) | 2 | 20.0 | 2060 | 0 | 1 | 1 |
| Sal k 1 1 (321-335) | 2 | 20.0 | 1947 | 1 | 0 | 1 | |