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. 2012 Jul 16;109(31):12698–12703. doi: 10.1073/pnas.1207219109

Fig. 2.

Fig. 2.

Activation phenotypes of MHC II−/− CD8 T cells in vivo. FACS-sorted naive Thy1.1 WT or MHC II−/− CD8 T cells were transferred into TCR-β−/− recipients. (A and B) CD25 and intracellular IL-2 expression (A) and CD8 T-cell IL-2 mRNA expression (B) were measured at 7 d after the transfer. Results shown are representative of between three and six individually tested recipients. (C and D) Surface CD5 expression was examined at 7 d posttransfer (C) or before transfer (D). Graphs show mean ± SD values of between four and six individually tested mice from two independent experiments. (E) Surface CD3ε expression on WT and MHC II−/− CD8 T cells was examined at 16 h posttransfer. The graph shows the mean ± SD of three individually tested mice. **P < 0.01; ***P < 0.001.