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. Author manuscript; available in PMC: 2013 Jul 26.
Published in final edited form as: Life Sci. 2012 Jun 19;91(1-2):54–63. doi: 10.1016/j.lfs.2012.06.005

Table 2.

Body weight, Heart Rate, Creatinine Clearance, Plasma Creatinine, and urinary excretion rate of Protein, NO metabolites (NOx), Hydrogen Peroxide (H2O2), and thiobarbituric acid reactive substances (TBARS) excretion in Placebo, Nebivolol, and Olmesartan treated rats. n=6–10.

Body weight (g) Heart
Rate
(beats/
min)		 Creatinine
Clearance
(ml/min)		 Plasma
Creatinine
(mg/dl)		 Urinary Protein
Excretion (mg/day)		 Urinary NOx
Excretion (µmol/day)		 Urinary
H2O2
Excretion
(µmol/day)		 Urinary
TBARS
Excretion
(nmol/day)
Baseline Week 6 Week 6 Week 6 Week 6 Baseline Week 6 Baseline Week 6 Week 6 Week 6
Placebo 377±14 374±10 339±17 2.1±0.8 1.0±0.3 24±6 307±121* 2.0±0.4 0.5±0.3* 0.14±0.03 113±25
Nebivolol 343±5 75±9* 301±3* 1.3 ± 0.7 0.7±0.1 28±4 213±36* 2.5±0.4 1.1±0.3* 0.20±0.01 121±19
Olmesartan 354±16 374±11 336±2 2.1 ± 0.4 0.6±0.1 21±4 84±16*+ 2.3±0.2 1.9±0.7 0.14±0.03 83±5
*

denotes p<0.05 vs respective baseline,

+

denotes p<0.05 vs Placebo at same time point.