Fig. (2).

A-F. Graphic representation of the “Effective Surface Area” of various modes of retinal laser treatment for retinal vascular disease. Vermillion = Retina unaffected by laser treatment. Brown = Area of retina destroyed by laser and inactive with respect to ability to produce extracellular cytokines. Yellow = Area of retina affected by the laser but not destroyed, able to contribute to the therapeutic effects of laser treatment via laser-induced alteration / normalization of cytokine expression. PASCAL = pattern scanning laser. MP = diode micropulse laser. SDM = “High density / low-intensity” subthreshold / subvisible diode micropulsed laser.