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. Author manuscript; available in PMC: 2012 Aug 6.
Published in final edited form as: J Pediatr. 2011 Jan 22;158(5):745–751. doi: 10.1016/j.jpeds.2010.10.043

Table 2.

Case-control analysis of NEC and sepsis outcomes in relation to secretor phenotype

Disease or control status Secretor Phenotype
Cases and controls n* No. Low H No. High H Odds Ratio (95% CI) P value**
Necrotizing enterocolitis (NEC)
NEC deaths 11 9 2 9.6 (1.9, 92) 0.001
Surgical NEC 14 9 5 3.8 (1.1, 15) 0.018
NEC cases 27 15 12 2.7 (1.1, 6.4) 0.019
Controls (NEC-free survivors) 363 112 251 1.0
Sepsis
Sepsis deaths 10 9 1 17.9 (2.4, 789) <0.001
Sepsis cases 91 31 60 1.03 (0.6, 1.7) 1.00
Controls (Sepsis-free survivors) 272 91 181 1.0
*

Salivary H phenotype was not determined for 27 infants missing a week 2 saliva sample, including 5 sepsis cases and 3 NEC cases.

**

The p-value was determined by 2-sided Fisher’s exact test comparing cases to controls.