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. 2012 Jun 22;9(8):2219–2227. doi: 10.1021/mp300073j

Figure 2.

Figure 2

Effect of TRAIL and E-selectin functionalized surfaces on viability of rolling Colo205. Percent viable cells after rolling over the functionalized surfaces for (A) 1 h and (B) 2 h as determined by the Annexin-V assay. (C) Representative flow cytometry plots. (D) Rolling delivery is time dependent. When Colo205 cells are perfused over the functionalized surface, an average kill rate of 12.91 ± 6.56 is observed while a kill rate of 41.88 ± 5.91 is observed when perfusing the cells for 2 h. (E) Cell death due to shear force experienced by Colo205 while passing through the microtube device. When compared to cells in culture, a gradual decrease in viability is seen with increased perfusion time. **p < 0.01, *p < 0.05, n = 3.